Cannanda CB2 Hemp Seed Oil (70 Vegan Softgels) on Sale

Description
Same as the liquid version of our CB2 Hemp Seed Oil, but now in a carrageenan-free VEGAN softgel format for those who prefer to take their oils as softgels instead of off a spoon.
We start with Cannanda s physician-formulated, multi-award-winning CB2™ terpene blend, and infuse it into pure Canadian-grown, certified-organic, cold-pressed hemp seed oil. Used for all the same reasons people use the CB2™ Wellness, but with the added benefits of the exact essential fatty acids that our body uses as building blocks for our own production of endocannabinoids.
While most use this as a legal, non-prescription alternative to cannabidiol (CBD), many also use this to enhance their CBD experience. CBD is the popular cannabis compound that has significant health benefits, but lacks the intoxicating effects of its sister compound, THC. This means you get a number of incredible health benefits without feeling high, and it delivers these benefits by positively influencing the endocannabinoid system (ECS; the body s master regulator of homeostasis).
Unfortunately, prior to legalization in Canada, CBD was only legally available by prescription only, or through black grey-market cannabis dispensaries. Even after legalization in late 2018, CBD continues to be legally available only through controlled distribution from licensed outlets.
By harnessing the power of terpenes in this precisely formulated blend, we can optimize the function of the ECS through activating one of its main receptors, a receptor called cannabinoid receptor type 2 (CB2).
However, if you re already CBD user, the benefits could be even greater! There is a perfect synergy between Cannanda s CB2 and CBD products (read more below).
World s First CB2 Agonist in a Carrageenan-Free VEGAN Softgel
Why? Carrageenan–sometimes listed as seaweed extract on labels–is a compound that causes inflammation.
In fact, in research studies on animals, scientists will often use carrageenan to induce inflammation (before administering and studying an anti-inflammatory compound). Why would anyone want this wreaking havoc through their intestinal tract, just to avoid animal gelatin?
Well, we ve gotten around this, and after years in development, finally bringing you a softgel version of our award-winning CB2 Hemp Seed Oil.
Activating the CB2 Receptor
CB2 is one of the two main receptors of the ECS. There are numerous benefits to activating this receptor without activating the CB1 receptor (the receptor THC activates, and is responsible for the high associated with cannabis). The following is a small list of studies illustrating the benefits of CB2 activation.
Pain & Inflammation;
- The CB2 receptor and its role as a regulator of inflammation (Cell Mol Life Sci. 2016; 73(23): 4449-70.)
-
- Targeting CB2 receptors and the endocannabinoid system for the treatment of pain (Brain Res Rev. 2009 Apr; 60(1): 255-266.)
-
- Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (Br J Pharmacol. 2008 Jan; 153(2): 319–334.)
-
- The central cannabinoid receptor type-2 (CB2) and chronic pain. (Int J Neurosci. 2017 Sep;127(9):812-823.)
-
Anxiety
- Anxious behavior induces elevated hippocampal CB2 expression. (Neuroscience. 2017 Jun 3;352:273-284.)
-
- Regulatory role of the CB2 receptor in stress-induced neuroinflammation. (Br J Pharmacol. 2014 Jun;171(11):2814-26.)
-
Degenerative neurological conditions
- Targeting cannabinoid CB2 receptors in the central nervous system. Medicinal chemistry approaches with focus on neurodegenerative disorders (Front Neurosci. 2016; 10: 406.)
-
- Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential (Neural Regen Res. 2016 Sep; 11(9): 1409–1410.)
-
-
CB2Â receptor: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)
-
- Cannabinoid CB2 receptors in human brain inflammation (Br J Pharmacol. 2008 Jan; 153(2): 277–285.)
-
Multiple Sclerosis:
-
CB2 receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (Br J Pharmacol. 2008 Jan; 153(2): 216–225.)
-
- Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. (J Neuroimmunol. 2017 Feb 15;303:66-74.)
-
Alzheimer s Disease
-
CB2 cannabinoid receptor as potential target against Alzheimer’s Disease (Front Neurosci. 2016; 10: 243.)
-
Parkinson s Disease
- Cannabinoid type 2 (CB2) receptors activation protects against oxidative stress and neuroinflammation associated dopaminergic neurodegeneration in rotenone model of Parkinson’s Disease (Front Neurosci. 2016; 10: 321.)
-
-
CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson’s disease (Exp Mol Med. 2016 Jan; 48(1): e205.)
-
Osteoarthritis:
- Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint (PLoS One. 2013; 8(11): e80440.)
-
- Expression of cannabinoid receptors in human osteoarthritic cartilage: Implications for future therapies (Cannabis Cannabinoid Res. 2016 Jan 1;1(1):3-15)
-
Rheumatoid arthritis:
-
CB2Â as a potential therapeutic target in rheumatoid arthritis (Musculoskeletal Disorders. 2014; 15: 275.)
-
-
CB2Â and its inhibitory effects on synovial fibroblasts in rheumatoid arthritis (Rheumatology. 2014; 53(5): 802-809.)
-
- Role of CB2 in mediating inflammation in rheumatoid arthritis synovial fibroblasts. (Clin Exp Rheumatol. 2019 Nov-Dec;37(6):1026-1035.)
-
Immune system modulation:
- CB2: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)
-
- Emerging role of the CB2 cannabinoid receptor in immune regulation and therapeutic prospects (Expert Rev Mol Med. 2009 Jan 20; 11: e3.)
-
Cardiovascular:
-
CB2Â
- The CB2 receptor and its role as a regulator of inflammation (Cell Mol Life Sci. 2016; 73(23): 4449-70.)
- Targeting CB2 receptors and the endocannabinoid system for the treatment of pain (Brain Res Rev. 2009 Apr; 60(1): 255-266.)
- Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (Br J Pharmacol. 2008 Jan; 153(2): 319–334.)
- The central cannabinoid receptor type-2 (CB2) and chronic pain. (Int J Neurosci. 2017 Sep;127(9):812-823.)
- Anxious behavior induces elevated hippocampal CB2 expression. (Neuroscience. 2017 Jun 3;352:273-284.)
- Regulatory role of the CB2 receptor in stress-induced neuroinflammation. (Br J Pharmacol. 2014 Jun;171(11):2814-26.)
- Targeting cannabinoid CB2 receptors in the central nervous system. Medicinal chemistry approaches with focus on neurodegenerative disorders (Front Neurosci. 2016; 10: 406.)
- Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential (Neural Regen Res. 2016 Sep; 11(9): 1409–1410.)
- CB2Â receptor: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)
- Cannabinoid CB2 receptors in human brain inflammation (Br J Pharmacol. 2008 Jan; 153(2): 277–285.)
-
CB2 receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (Br J Pharmacol. 2008 Jan; 153(2): 216–225.)
- Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. (J Neuroimmunol. 2017 Feb 15;303:66-74.)
-
CB2 cannabinoid receptor as potential target against Alzheimer’s Disease (Front Neurosci. 2016; 10: 243.)
- Cannabinoid type 2 (CB2) receptors activation protects against oxidative stress and neuroinflammation associated dopaminergic neurodegeneration in rotenone model of Parkinson’s Disease (Front Neurosci. 2016; 10: 321.)
- CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson’s disease (Exp Mol Med. 2016 Jan; 48(1): e205.)
- Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint (PLoS One. 2013; 8(11): e80440.)
- Expression of cannabinoid receptors in human osteoarthritic cartilage: Implications for future therapies (Cannabis Cannabinoid Res. 2016 Jan 1;1(1):3-15)
-
CB2Â as a potential therapeutic target in rheumatoid arthritis (Musculoskeletal Disorders. 2014; 15: 275.)
- CB2Â and its inhibitory effects on synovial fibroblasts in rheumatoid arthritis (Rheumatology. 2014; 53(5): 802-809.)
- Role of CB2 in mediating inflammation in rheumatoid arthritis synovial fibroblasts. (Clin Exp Rheumatol. 2019 Nov-Dec;37(6):1026-1035.)
- CB2: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)
- Emerging role of the CB2 cannabinoid receptor in immune regulation and therapeutic prospects (Expert Rev Mol Med. 2009 Jan 20; 11: e3.)
- CB2Â
Cardiovascular:
Immune system modulation:
Rheumatoid arthritis:
Osteoarthritis:
Parkinson s Disease
Alzheimer s Disease
Multiple Sclerosis:
Degenerative neurological conditions
Anxiety